The Comparison of Changes of QTc, Tp-e Interval, and Tp-e/QT Ratio, Tp-e/QTc Ratio on the ECG During Robotic-assisted Laparoscopic Radical Prostatectomy Under Sevoflurane, Desflurane and Total Intravenous Anesthesia -Randomized Controlled Trial

• Status: Completed
• Trial end date: 2019-01-22
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to compare the changes of QTc, Tp-e interval, and Tp-e/QT ratio, Tp-e/QTc ratio on the ECG during robotic-assisted laparoscopic radical prostatectomy under sevoflurane, desflurane and total intravenous anesthesia

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Anesthetics; Desflurane; Isoflurane; Propofol; Remifentanil; Sevoflurane

Criteria

Inclusion Criteria:

1. ASA class I-III

2. patients undergoing elective robot-assisted laparoscopic radical prostatectomy

3. adult (≥19 years old)

Exclusion Criteria:

1. emergency surgery

2. preoperative QTc prolongation

3. Cardiac disease (unstable angina, congestive heart failure, valvular heart disease)

4. uncontrolled hypertension (DBP >110 mmHg)

5. Patients who take beta blocker

6. Ventricular conduction abnormality

7. Hepatic or renal failure

8. Drug hyperactivity

9. patients unable to understand informed consent (foreigner, illiteracy..)