The Comparison of Different Administration Routes of Pediatric Premedication

• Status: Unknown status
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study purpose is to compare the effect of different Administration Routes of Pediatric Premedication (including oral administration, intramuscular injection, rectal perfusion, intranasal).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University
• Treatments: Anesthetics; Atracurium; Atropine; Fentanyl; Ketamine; Midazolam; Propofol

Criteria

Inclusion Criteria:

• Informed consent of children's parents;

• Children patient in pediatric surgery and E.N.T. department;

• surgery time 1 ~ 3 hours;

• Aged between 1 and 7 years old;

• American Society of Anesthesiologists (ASA)classification:class I~II;

Exclusion Criteria:

• With cardiovascular and respiratory complications;

• A history of the endocrine system;

• A long history of application of sedative drugs;

• Water and electrolyte balance disorder preoperatively;

• Liver and kidney dysfunction;

• Nervous system dysfunction;

• High gastrointestinal obstruction;

• Tracheoesophageal fistula, trachea foreign body, hiatal hernia, dysphagia;

• Lung infection, atelectasis;

• Congenital heart disease(CHD);

• Severe malnutrition;

• Traumatic or ischemia anoxic encephalopathy, high cranial pressure;

• Anesthesia and surgery was conducted in 3 days;