The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol

• Status: Completed
• Trial end date: 2010-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to compare the efficacy for cervical ripening in labor induction between titrated and conventional oral misoprostol

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mahidol University
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• age 18 years old or more

• singleton pregnancy at 37 weeks gestation or more

• cephalic presentation

• reassuring fetal heart rate pattern

• admission for labor induction due to medical or obstetrical conditions

• bishop score less than 6

• giving consent and having signed the consent form for this study

Exclusion Criteria:

• parity more than 3

• estimated fetal weight more than 3,500 grams

• non-reassuring fetal heart rate pattern

• having contraindication for vaginal delivery

• previous uterine scar

• suspected abruptio placenta with non-reassuring fetal heart rate pattern

• abnormal bleeding per vagina, except bloody show

• PROM

• having underlying cardiac, hepatic, or renal diseases

• having history of allergy to misoprostol or prostaglandin analogues

• cervical dilatation 3 centimeters or more

• uterine contraction 3 times or more in 10 minute