The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
Status:
Completed
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
During induction for cardiac surgery, patient hemodynamic stability is achieved by using
anesthetic drugs which least affects hemodynamics such as benzodiazepines, etomidate.
Etomidate although has been used for a long time but its safety regarding cortisol synthesis
suppression is still doubtful. This study measures the changes in cortisol levels during
cardiac surgery with the use of cardiopulmonary bypass by comparison between two inductive
agents (etomidate and thiopentone). Recording data also include hemodynamic changes during
induction, inotropic use for coming of cardiopulmonary bypass, blood glucose levels, amount
of insulin usage, length of ICU and hospital saty.