The Difference in the Mechanism of Action Between Two Brands of Dexamfetamine in Adults With ADHD
Status:
Not yet recruiting
Trial end date:
2023-06-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare in the pk/pd profiles of magisterial
dexamfetamine and Tentin in adults with Attention Deficit Hyperactivity Disorder (ADHD). The
main question[s] it aims to answer are:
Q1: is there a difference between pk/pd profiles of the two forms of dexamfetamine?
Q2: how does the pharmacokinetic variability influences the objective and subjective (side)
effects experienced by adult patients with ADHD?
Participants will:
- take the Quantified behavior Test for analysis of objective effects.
- undergo blood sampling for analysis of the plasma concentration of dexamphetamine.
- undergo blood pressure and heart rate measurements.
- fill out 4 types of questionnaires.
Researchers will compare the outcomes between magisterial dexamphetamine and Tentin use in a
crossover setting.
Phase:
N/A
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)