The Dose Response of Prednisone on Biochemical and Clinical Makers in Adult Healthy Volunteers

• Status: Completed
• Trial end date: 2006-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to further access the utility of biochemical and clinical biomarkers for glucocorticoid-mediated anti-inflammatory effects and safety endpoints against which dissociated agonists of the glucocorticoid receptor (DAGR) will be evaluated in adult healthy volunteers.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pfizer
• Treatments: Prednisone

Criteria

Inclusion Criteria:

• Healthy male or females willing to be confined and comply with scheduled visits

• Women are to be surgically sterile.

Exclusion Criteria:

• History of febrile illness within 5 days prior to the first dose

• Positive urine drug screen

• Treatment with an investigational product within 30 days prior to the first dose of study medication