The Effect Of Omega-3 Fatty Acids on Non-alcoholic Fatty Liver Disease

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

There is preliminary evidence that Omega 3, a compound naturally found in fish oil, reduces the amount of fat stored in the liver and improves liver function. The purpose of this study is to see whether this observation is correct.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Edinburgh
• Collaborator: NHS Lothian

Criteria

Inclusion Criteria:

• a diagnosis of non-alcoholic fatty liver disease

• fatty infiltration on ultrasound

• abnormal serum liver function tests.

Exclusion Criteria:

• any other identified cause of chronic liver disease

• the prescription of medication which would cause non-alcoholic fatty liver - disease (e.g. tamoxifen)

• already taking supplementary fish oil

• alcohol intake of >20g/day for women, >40g/ day for men

• known allergy to fish oil

• on anticoagulants (antiplatelets are permitted)

• severe heart failure (NYHA class IV)

• pregnancy/ lactation

• age under 18 years.