The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular Teeth
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Simvastatin has been reported to promote osteoblastic activity and inhibit osteoclastic
activity by enhancing the expression of BMP2. There have been many studies demonstrating the
bone-promoting effect of local application various animal models including after application
into socket of teeth in a rat. the purpose of the study is to investigate the effect of slow
release topical simvastatin in socket of mandibular teeth on bone remodeling in the socket