The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to
evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous
stomatitis (RAS). To be included in the study, subjects must have had minor RAS ulcers of
less than 48 hours duration. It was randomly determined which powder was used first; all
subjects used both the 2-DeNT powder and the placebo powder. Subjects applied the powder
twice daily and maintained a daily log recording the size of the ulcer, its erythema score,
and their level of pain. The subjects continued applying the 2-DeNT powder until the ulcer
was resolved.