Overview

The Effect of Age on the Median Effective Dose (ED50) of Intranasal Dexmedetomidine for Rescue Sedation Following Failed Sedation With Oral Chloral Hydrate During Magnetic Resonance Imaging

Status:
Completed

Trial end date:
2016-03-01

Target enrollment:

Participant gender:

Summary

Increasing evidences suggest that dexmedetomidine Pharmacokinetic are different in children. We performed a up-down sequential allocation study to determine the ED50 for rescue sedation following sedation failures in children and to investigate age-related differences in the rescue sedation with dexmedetomidine.

Phase:

Phase 4

Details

Lead Sponsor:

Guangzhou Women and Children's Medical Center

Treatments:

Chloral Hydrate
Dexmedetomidine