The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)

• Status: Completed
• Trial end date: 2020-11-19
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes to the wide variation in neurologic recovery and developmental outcome after surgery in infants with congenital heart disease.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Stanford University
• Collaborator: The Gerber Foundation
• Treatments: Anesthetics; Dexmedetomidine; Fentanyl; Isoflurane; Narcotics

Criteria

Inclusion Criteria:

• Neonates of at least 32 weeks of gestation, infants and children up to 2 years of age admitted to The Children's Hospital for treatment of cyanotic or non-cyanotic heart disease requiring surgical intervention.

• Admitting diagnosis of cyanotic or non-cyanotic heart disease

Exclusion Criteria:

• Neonates less than 32 weeks of gestational age, and children more than 2 years of age.

• Any documented central nervous system malformations.

• Any potential subject requiring unexpected postoperative Extracorporeal membrane oxygenation (ECMO) support