The Effect of Anesthetics on Oxidative Stress and Apoptosis Status in Children

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to determine whether Propofol and Sevoflurane affect the oxidative stress and apoptosis status in children undergoing hypospadias repair surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: First Affiliated Hospital, Sun Yat-Sen University
• Treatments: Anesthetics; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• American Society of Anesthesiology (ASA) I-II, undergoing selective surgery for hypospadias repair.

Exclusion Criteria:

• a history of developmental delay or mental retardation, which could make observational pain intensity assessment outside the norm;

• a history of central nervous system diseases;

• a known or suspected coagulopathy;

• a known allergy to any of the study drugs;

• abnormalities of the sacrum and any signs of infection at the site of the proposed caudal block.