The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients

• Status: Completed
• Trial end date: 2005-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effects of the anticholinesterase drug donepezil on sleep in Alzheimer disease patients. Sleep structure and respiratory parameters will be analyzed by polysomnography.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Associacao Fundo de Incentivo a Psicofarmcologia
• Collaborator: Fundação de Amparo à Pesquisa do Estado de São Paulo
• Treatments: Cholinesterase Inhibitors; Donepezil

Criteria

Inclusion Criteria:

• Diagnosis of Alzheimer's disease based on the probability criteria of the Alzheimer's Disease and Related Disorders Association

• Rated 1 and 2 (mild to moderate level) on the Brazilian version of the Clinical Dementia Rating

Exclusion Criteria:

• Other causes of dementia

• Other severe medical or psychiatric disease

• Clinical indication of psychoactive drugs other than experimental drug