The Effect of Azithromycin in the Treatment of Chronic Periodontitis

• Status: Completed
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to investigate the effects of Azithromycin (systemic and locally) on the clinical and microbiological parameters of periodontal in patients with chronic periodontitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Isfahan University of Medical Sciences
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Azithromycin

Criteria

Inclusion Criteria:

1. Patients with moderate to severe chronic periodontitis

2. At least twenty teeth

3. Age over 18 years

Exclusion Criteria:

1. With Systemic diseases that affect periodontal conditions such as: diabetes, blood disorders and diseases of immune system

2. History of antibiotic therapy within the 4 months prior to study

3. History of Allergy to the macrolide group of antibiotics

4. Smoking

5. The lack of patient cooperation

6. History of periodontal treatment during the 4 months prior to the trial

7. Pregnancy

8. Lactating females

9. Patients treated with drugs such as: Anti-acid, Warfarin and Cyclisporine 10) Alcohol use.