The Effect of Bowel Preparation on Perioperative Bleeding

• Status: Completed
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Now a days, due to the change in lifestyle, the extended lifespan and the increase in the rate of the road accidents, the need for surgical operation of spinal instrumentation has been increased. And these surgeries are the most crucial part of neurological surgery wards. The everyday improvements in the quality of equipment used and advancements in surgical methods lead to best performance of these procedures and finally the higher quality of patients' lives. The procedures of Laminectomy and pedicular screw instrumentation lead to pain relief and better performance and developments in the quality of patients' lives.

In addition to the above mentioned improvements, you must consider the fact that these activities are still accompanied by complications during and after surgical operation.

Nerve root injury, Thecal sac tearing, injury to the spinal cord and the inappropriate sagittal balance are the most significant side effects during spinal surgery.

One of the most important complications during and after these surgeries is perioperative bleeding that causes problems both for the patients and the surgeon.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Isfahan University of Medical Sciences
• Treatments: Cefazolin

Criteria

Inclusion Criteria:

• Patients who suffer from lumbar spine degenerative disease and need spine fusion surgery.

Exclusion Criteria:

• History of Trauma,

• History of Malignancy,

• previous spinal surgery,

• History of coagulation disorder,

• active infectious disease,

• gastrointestinal problems,

• severe movement disorders.