Overview

The Effect of Chlorzoxazone on Moderate to Severe Postoperative Pain After Spine Surgery

Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. Our purpose is to investigate the effect of chlorzoxazone on moderate to severe postoperative pain after spine surgery. Our hypothesis is that chlorzoxazone can reduce postoperative pain and reduce opioidconsumption and side effects compared to placebo.
Phase:
Phase 4
Details
Lead Sponsor:
Rigshospitalet, Denmark
Collaborator:
Glostrup University Hospital, Copenhagen
Treatments:
Chlorzoxazone
Morphine
Ondansetron