The Effect of Choice of Intraoperative Opioid on Postoperative Pain
Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
The primary aim of this randomized, double-blind study is to examine the effect of a single
intraoperative dose of methadone on postoperative pain and analgesic requirements in patients
undergoing cardiac surgery with cardiopulmonary bypass. These patients will be compared to
subjects receiving a standard dose of the "traditional" intraoperative opioid (fentanyl).
Secondary outcome measures to be assessed will include standard recovery variables (such as
length of postoperative intubation, ICU length of stay, incidence of nausea or vomiting,
level of sedation). In addition, patients will be assessed for the development of chronic
postoperative pain.
Phase:
Phase 4
Details
Lead Sponsor:
NorthShore University HealthSystem NorthShore University HealthSystem Research Institute