The Effect of Cyclosporin Before Cataract Surgery

• Status: Not yet recruiting
• Trial end date: 2021-06-11
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the effect of cyclosporine eye drop before cataract surgery for the prevention of post cataract surgery dry eye syndrome.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Samsung Medical Center
• Treatments: Cyclosporine; Cyclosporins

Criteria

Inclusion Criteria:

1. 21+ adult men and women

2. Those who are scheduled to undergo cataract surgery due to a diagnosis of cataract

3. Corneal fluorescein staining score (Oxford) is II or less

4. Preoperative MMP-9 positive

5. Those who have not used the trial and the test (cyclosporine) for at least 1 month before surgery.

6. Those who have voluntarily written consent to participate in this clinical trial

Exclusion Criteria

1. Those who have used systemic or topical cyclosporine within 4 weeks

2. Use of eye drops for more than 4 weeks (disorders, allergies, eye inflammation / infection, etc.) other than the current dry eye syndromes

3. Patients who have systemic or ocular disorders or conditions (eye surgery, trauma, disease) that can influence the results of this trial.

4. Abnormal eyelid function

5. An eye disease that can impair the function of the corneal sensation: herpes keratopathy, conjunctival wounds due to scarring conjunctivitis, pterygium, pinguecula, diabetic keratitis, keratoconus , corneal transplant status

6. Patients with active eye infections

7. Patients with conflicts with this clinical trial

8. Pregnant and lactating mothers

9. Patients who are determined to be inappropriate by other investigators