The Effect of Daily Tamsulosin 0.2mg Administration on Renal Function in Patients With Benign Prostatic Hyperplasia

• Status: Unknown status
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to determine whether medical treatment for bladder outlet obstruction is effective in improvement of glomerular filtration rate and/or proteinuria.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Catholic University of Korea
• Treatments: Tamsulosin

Criteria

Inclusion Criteria:

• Men with low urinary tract symptoms aged between 40 and 80

• Estimated glomerular filtration rate < 60 or evidence of proteinuria

• Bladder outlet obstruction index > 40, Schäfer grade 2 or more, maximal flow rate lower than 10 cc/s or postvoid residual urine > 100cc

Exclusion Criteria:

• Bladder outlet obstruction index less than 40, Schäfer grade 0 or 1, maximal flow rate higher than 10 ml/s and postvoid residual urine less than 100cc

• Want surgical procedure

• Evidence of prostate cancer or bladder cancer

• Major depressive disorder, Dementia, Parkinson's disease or neurological deficits

• History of pelvic irradiation

• Uncontrolled diabetes mellitus or hypertension

• Symptomatic orthostatic hypotension