The Effect of Decreasing the Inspired Oxygen Concentration on Post-Operative Oxygenation After Primary Lobectomy

• Status: Withdrawn
• Trial end date: 2018-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test the hypothesis that decreasing the inspired oxygen concentration during thoracic surgery requiring one lung ventilation will improve post-operative oxygenation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yale University

Criteria

Inclusion Criteria:

1. Adults, 18 years of age and older, male or female.

2. American Society of Anesthesiology (ASA) physical status I, II, III or IV

3. Subjects who are scheduled for elective primary pulmonary lobectomy.

4. Subjects who have an arterial line placed as part of routine anesthetic management

5. Subjects who can understand and communicate in English.

Exclusion Criteria:

1. Subjects with a history of difficult intubation

2. Subjects with a high risk of aspiration during induction of anesthesia

3. Subjects with morbid obesity (BMI greater than or equal to 40)

4. Subjects with unable to provide consent

5. Subjects who are minors

6. Subjects who are not English speaking