The Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic Gastrectomy
Status:
Completed
Trial end date:
2017-06-16
Target enrollment:
Participant gender:
Summary
This study is a multicenter, randomized, controlled, double-blinded, and parallel design
study. A total of 96 patients were decided to be recruited considering a 10% dropout rate.
Patients are randomized to receive a deep block or a moderate block. The randomization
numbers are generated using a computer-generated randomization code (1) and are sealed in the
opaque envelope until they are handed over to the anesthesiologist in charge of anesthesia
management after the induction of anesthesia. Patients, surgeons reporting the scale of
surgical status, and another researcher analysing the cytokines levels are blinded to the
patient group. Patients aged 18-65 yr, ASA 1 or 2, and are scheduled for elective
laparoscopic gastrectomy are included. Patients with severe respiratory or cardiac disease,
hepatic or renal function impairment, on medications affecting neuromuscular function, and
with known allergy to the drugs to be used are excluded.