The Effect of Dexamedetomidine for Interscalene Brachial Plexus Block on Plasma Biomarkers After Rotator Cuff Repair

• Status: Completed
• Trial end date: 2016-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study was designed to test the hypothesis that dexmedetomidine added to ropivacaine for interscalene brachial plexus blocks for elective shoulder surgery would enhance the duration and effect of analgesia when compared with ropivacaine alone, and their influence on serum IL-6, cortisol, IL-1beta, IL-8, and substance p.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Chuncheon Sacred Heart Hospital
• Treatments: Dexmedetomidine; Ropivacaine

Criteria

Inclusion Criteria:

1. a definite rotator cuff tear that needed repair seen on preoperative magnetic resonance imaging

2. acceptance of arthroscopic surgery including rotator cuff repair

3. age more than 20 years,

4. acceptance of preemptive regional block , PCA and blood sampling after 1 ,6, 12, 24, 48 hour postoperatively. .

Exclusion Criteria:

1. they did not undergo arthroscopic rotator cuff repair

2. they stopped PCA before 48 hours postoperatively because of associated side effects

3. there was a history of a previous shoulder operation or fracture

4. there was a concomitant neurologic disorder around the shoulder

5. refusal of blood sampling.