The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine

• Status: Terminated
• Trial end date: 2010-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics.. Participants will be patients undergoing shoulder surgery with an interscalene nerve block.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Outcomes Research Consortium; The Cleveland Clinic
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• Age between 18 and 75 years

• Patients undergoing shoulder procedures, such as rotator cuff repair, capsular shift, shoulder arthroplasty, subacromial decompression

Exclusion Criteria:

• Contraindications to interscalene block (Coagulopathy, infection at the needle insertion site, moderate to severe chronic obstructive pulmonary disease, contralateral pneumothorax or diaphragmatic paralysis)

• Pregnancy

• Pre-existing neuropathy involving the surgical limb

• Systemic glucocorticoid treatment (for 2 weeks or more) within six months of surgery

• Chronic opioid use (greater than 30 mg oral oxycodone equivalent per day)