The Effect of Dexmedetomidine, Melatonin and Pregabalin

• Status: Not yet recruiting
• Trial end date: 2024-11-20
• Target enrollment: 0
• Participant gender: All

Summary

Various drugs have been used for the purpose: nitroglycerine, sodium nitroprusside, propofol, beta blockers, calcium channel blockers, higher concentrations of inhalational anesthetics etc. Since all these drugs have certain limitations there was a search for more safe and effective drug

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Egymedicalpedia
• Treatments: Dexmedetomidine; Melatonin; Pregabalin

Criteria

Inclusion Criteria:

• Patients undergoing Functional endoscopic sinus surgery (ASA I & II)

Exclusion Criteria:

• Hepatic, renal, endocrinal, hematological disorders.

• BMI>30 kg/m2.

• Patients receiving magnesium supplementation, anticonvulsant drugs or antipsychotic drugs.

• Chronic use of opioids.

• Current treatment with β-blocker or calcium channel blocker.

• Known allergies to any of study drugs.

• Patients refusal to the study