The Effect of Dexmedetomidine on Propofol Requirement for Insertion of Laryngeal Mask Airway
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
Propofol frequently used as an inducting medication for insertion Laryngeal mask airway(LMA).
But propofol alone can be not sufficient for inhibiting upper airway reflex and also result
in cardiovascular suppression under enough amount. Dexmedetomidine is a selective alplh2
receptor agonist with analgesic and sedative effects but sparing respiratory function.
Therefore propofol combined with dexmedetomidine induction could be more effective in
preserve respiration under same condition for LMA insertion than propofol alone. In this
study, the investigators investigate the clinical dose of propofol for LMA insertion with
premedication of dexmedetomidine, and evaluate the effect of dexmedetomidine.