The Effect of Docetaxel or Gemcitabine-based Chemotherapy in East Asian and Caucasian Patients
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
The aims of this study are:
1. to compare the toxicity profile and efficacy of gemcitabine/carboplatin or docetaxel in
East Asian and Caucasian patients.
2. to determine the genotype distribution of genes involved in docetaxel and gemcitabine
pathways in East Asian and Caucasian patients.
3. to evaluate the association between genotypes and
1. treatment toxicity
2. treatment efficacy
3. pharmacokinetics.