The purpose of this study is to evaluate the use of electroretinogram (ERG) using a novel
handheld system, RETeval, and evaluate contrast sensitivity testing in detecting pre-clinical
retinopathy on a tablet device.
Investigators also seek to assess if a medication called Sinemet™ CR can improve the
electrical functions of the eye in participants with diabetes mellitus. This study will
include a total of 45 participants; 30 with diabetes mellitus and 15 age-matched non-diabetic
controls. Participants with diabetes mellitus and electroretinogram (ERG) delays will be
randomized to a low or high dose Sinemet CR group.
Phase:
Phase 1
Details
Lead Sponsor:
Emory University
Treatments:
Carbidopa Carbidopa, levodopa drug combination Dopamine Levodopa