The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men
Status:
Completed
Trial end date:
2007-01-01
Target enrollment:
Participant gender:
Summary
Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence
world wide with an increased risk of myocardial infarction and stroke. GLP-1 has convincing
effects on the high glucose levels in type 2 diabetic patients and is well tolerated. New
animal studies indicate a protective effect of GLP-1 in the brain and the heart. The
mechanism behind this is yet not known.
The study hypothesis is that GLP-1 will stimulate glucose-uptake in the brain and heart
independent of insulin and thereby exert its protective effects.