The Effect of Gut Sterilisation on Macrophage Activation in Patients With Alcoholic Hepatitis.
Status:
Completed
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
Alcoholic hepatitis (AH) is a severe alcohol induced hepatic inflammation that leads to
jaundice and liver failure. Gut derived bacterial translocation to the liver is currently
thought to be one of the main inflammatory drivers of the disease.
This project investigates the effects of gut sterilisation with broad spectrum antibiotics in
patients with AH