The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF

• Status: Not yet recruiting
• Trial end date: 2023-02-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is to assess the efficacy of intraoperative intravenous nonsteroidal anti-inflammatory drug (ketorolac) versus intravenous (dexamethosone) administration on dysphagia and dysphonia after ACDF.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Nebraska
• Treatments: Dexamethasone; Ketorolac

Criteria

Inclusion Criteria:

• 19 years of age and older

• Undergoing ACDF for radiculopathy or myelopathy

• No known allergies or sensitivities to steroid or non-steroidal medications

Exclusion Criteria:

• Procedure is being done for revision, trauma, infection or tumor

• Patients with known diagnosed metabolic diseases (diabetes, pancreatitis, gout, electrolyte imbalances, hypertension, hematological abnormalities including gastrointestional bleeding...)

• Patients with known kidney disease or a creatinine level above the upper limit of normal >1.27