The Effect of Inhaled Corticosteroids on Vocal Fold Nodules in Children

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Voice disorders are the most common communication disorder across the lifespan and vocal fold nodules are the most frequent pathology affecting voice in children. The goal of the present study is to determine the safety and feasibility of a short-course of inhaled corticosteroids in addition to standard voice therapy for treating vocal fold nodules.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Joseph Dohar, MD; University of Pittsburgh
• Treatments: Fluticasone; Xhance

Criteria

Inclusion Criteria:

• Newly diagnosed with vocal fold nodules;

• Considered behaviorally and cognitively appropriate by PI for voice therapy;

• English comprehension and production sufficient to participate in the protocol and in voice therapy;

• Not currently on inhaled corticosteroids;

• No previous voice therapy;

• Willing to participate in voice therapy at Children's Hospital of Pittsburgh

Exclusion Criteria:

• Other medical conditions or medications that would mask or amplify voice outcomes, including developmental or other neuromuscular conditions, major illness or disorders, chronic or acute with the exception of laryngopharyngeal reflux disease or allergies and their treatments.