The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in Interstitial Lung Disease.
Status:
Not yet recruiting
Trial end date:
2023-06-01
Target enrollment:
Participant gender:
Summary
Interstitial Lung Disease (ILD) is a is a lung disorder which makes breathing more difficult.
During exercise, patients with ILD are not efficient breathers and this leads to serious
breathing difficulties, which often causes these patients to stop exercise at low
intensities. The investigators think that these patients with ILD have problems exchanging
fresh gas (i.e., oxygen) into the blood stream because of poor lung blood vessel function.
The investigators will test whether inhaled medications, specifically nitric oxide, can
improve lung blood vessel function and decrease breathing difficulties during exercise. With
this research, the investigators will understand more about breathing efficiency and lung
blood vessel function in mild ILD patients, and find out whether improving lung blood vessel
function helps ILD patients breathe easier and exercise longer. Understanding the reasons
behind the feeling of difficult breathing may lead to more effective therapy and improved
quality of life in ILD patients.