The Effect of Intraoperative Infusion of Dexmedetomidine Versus Low Dose Ketamine

• Status: Recruiting
• Trial end date: 2023-12-20
• Target enrollment: 0
• Participant gender: All

Summary

Comparing between dexmedetomidine versus low dose ketamine infusion in patients undergoing nasal and paranasal sinus surgery as regard, intraoperative hemodynamic stability, blood loss, perioperative opioid requirements, Stress response evaluation through the measurement of serum level of cortisol, IL-6, blood glucose and CRP.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Al-Azhar University
• Treatments: Dexmedetomidine; Ketamine

Criteria

Inclusion Criteria:

• • Between 21 and 40 years of age, they with American Society of Anesthesiologists (ASA) physical status I-II and undergoing nasal and paranasal sinus surgery.

Exclusion Criteria:

• • Refusal to join the study.

• Allergy to the drugs used in the study.

• Drug and/or alcohol abuse.

• Mental and psychiatric disorders.

• Emergency operations.

• Patients with systemic illnesses (eg, hypertension [ SBP >160 mm Hg], diabetes mellitus.