The Effect of Intravenous Acetaminophen on Post-Operative Pain After Craniotomy
Status:
Completed
Trial end date:
2017-11-01
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine the efficacy of IV acetaminophen when administered
to neurosurgical patients at the beginning and end of their surgery. If the result is
improved pain control with less opioid consumption postoperatively, then those patients may
also experience less opioid related side effects such as nausea/vomiting, pruritus, and
sedation. While numerous other studies have failed to show a benefit of IV acetaminophen
after neurosurgical procedures, we are studying the administration of 1 g in two doses over
the course of the operation.