The Effect of Intravenous Lidocaine on Normal Sensation and Pain in Healthy Volunteers

• Status: Completed
• Trial end date: 2012-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to study if lidocaine, given intravenously, reduces pain.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Alabama at Birmingham
• Collaborator: American Society of Regional Anesthesia
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Healthy Adult Volunteers, age >19 years

Exclusion Criteria:

• History of Substance Abuse

• Coronary Artery Disease (CAD): unstable

• Congestive Heart Failure (CHF): unstable

• Heart Arrhythmia: symptomatic

• Chronic Obstructive Pulmonary Disease (COPD)

• Lidocaine Allergy

• Diagnostic and Statistical Manual of Mental Disorders (Rev IV): Axis I: Common Axis I disorders include depression, anxiety disorders,bipolar disorder, ADHD, and schizophrenia. Axis II: borderline personality disorder, schizotypal personality disorder, antisocial personality disorder, and mild mental retardation.

• Presence of Contraindications for MRI

• Presence of electronically, magnetically, and mechanically activated implants

• Electronically, magnetically, and mechanically activated implants

• Ferromagnetic or electronically operated active devices like automatic cardioverter defibrillators

• Cardiac pacemakers

• Metallic splinters in the eye

• Ferromagnetic haemostatic clips in the central nervous system (CNS)

• Claustrophobia

• Pregnancy