The Effect of Intravenous Lidocaine on Post-extubation Laryngospasm

• Status: Terminated
• Trial end date: 2012-04-01
• Target enrollment: 0
• Participant gender: All

Summary

In the literature, we found no randomized clinical trials addressing the using of IV lidocaine as prophylaxis for postoperative laryngospasm among adults.

The aim of this study was to assess the effects of IV lidocaine on the incidence of postoperative laryngospasm of adults patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: King Saud University
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• American Society of Anesthesia score are I or II

• Undergo for laparoscopic cholecystectomy

Exclusion Criteria:

• Patient's refusal

• History of upper respiratory tract infection (URTI) within 2 weeks

• Persistent type of hyper-reactive airway or asthma

• History of airway surgery

• History of gastro-esophageal reflex disease (GERD)

• Currently receiving sedating or analgesic medication

• Currently receiving the following medications:

• Fluvoxamine

• Erythromycin and Itraconazole

• β -blocker or Cimetidine

• History of Lidocaine Allergy

• History of epilepsy disorder

• Pregnant or breastfeeding women

• History of Heavy Smoking ( a smoker with a daily cigarettes consumption of more than 20 pieces

• History of increased salivation by a disease or medication

• History of difficult intubation

• Two or more attempts of intubation