The Effect of Isoflurane or Sevoflurane on Kidney Function

• Status: Terminated
• Trial end date: 2005-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if isoflurane and sevoflurane have similar effects on the kidneys of people with impaired kidneys when the drugs administered with low gas flow into anaesthetic machines.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Austin Health
• Treatments: Isoflurane; Sevoflurane

Criteria

Inclusion Criteria:

Adult patients for elective surgery who will:

• Need to stay at least one night, and

• Need general anaesthesia, and

• Have a pre-operative serum creatinine concentration greater than 130 umol/l.

Exclusion Criteria:

• The patient refuses.

• The patient is less than 18 years of age.

• The patient is on pre-operative dialysis

• The anaesthetist plans to use only regional or total intravenous anaesthesia.

• Specific types of surgery: craniotomy, carotid, and cardiac.