The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection
Status:
Unknown status
Trial end date:
2020-07-01
Target enrollment:
Participant gender:
Summary
Systemic inflammation caused by surgery may aggravate immunosuppression in immunocompromised
cancer patients. The natural killer (NK) cell is a critical part of anti-tumor immunity.
ketamine, a N-methyl-D-asparate receptor antangonist, has anti-inflammatory activity and
opioid-sparing effect. This study investigate the effect of intraopertaive ketamine
administration on immune function in patients undergoing laparoscopic colorectal cancer
resection.