The Effect of Local Anesthetic Volume Within the Adductor Canal on Quadriceps Function Evaluated by Electromyography

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

Our aim is to investigate which components of the quadriceps femoris muscle are affected following an ACB with different volumes (10, 20 and 30 ml) of 1% lignocaine evaluated by electromyography. Both a placebo treatment (20ml saline) and the femoral nerve block (20ml lignocaine 1%) as an active comparative will be used for model control. Further, we want to investigate the effect of volume on motor block. This will be evaluated by measuring the Maximum Voluntary Isometric Contraction (MVIC) of the quadriceps femoris muscle.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ulrik Grevstad
• Treatments: Anesthetics; Anesthetics, Local; Lidocaine

Criteria

Inclusion Criteria:

• Age > 18 years old

• Subjects who gave their written informed consent to participating in the study after having fully understood the contents of the protocol and re-strictions.

• ASA 1

• Male

• BMI 18-30

• Physical exercise 1-3 hours/week

Exclusion Criteria:

• Subjects who cannot cooperate with the study.

• Subjects who cannot understand or speak Danish.

• Subjects with allergy to the medicines used in the study.

• Subjects suffering from alcohol and/or drug abuse - based on the investi-gator's opinion.

• Pathology or previous surgery or trauma to the lower limb.

• Intense exercise 24 h before the tests

• Intake of any analgesics 24 h prior to baseline measurements.