The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317)

• Status: Completed
• Trial end date: 2006-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will qualify a functional model that can measure central blood pressure and vascular compliance effects through noninvasive means.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Merck Sharp & Dohme Corp.
• Treatments: Isosorbide; Isosorbide Dinitrate; Isosorbide-5-mononitrate; Losartan

Criteria

Inclusion Criteria:

• Patient is in good health with the exception of mild to moderate hypertension

• Patient is willing to comply with the study restrictions

• Patient does not smoke

Exclusion Criteria:

• Patient has a history of any illness that might confound the results of the study or make participation in the study unsafe

• Patient is taking a prescription medication that is contraindicated for use with COZAAR® or IMDUR®

• Patient has a condition for which there is a warning, contraindication, or precaution against the use of COZAAR® or IMDUR®