The Effect of Magnesium Use in Reversal of Neuromuscular Block With Sugammadex

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Magnesium therapy used for seizure prophylaxis in patients with preeclampsia. Magnesium has been shown to prolong the effect of nondepolarizing neuromuscular blocking agents (NMBA) and neostigmine used to reverse the effect of NMBA in general anesthesia . In this study, the investigators aimed to evaluate time from sugammadex injection to Train-of-four ratio 0.9 who receieved magnesium therapy in reversing the effect of neuromuscular blocking agent during the recovery period and the relationship between magnesium level and duration of action of sugammadex

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Eskisehir Osmangazi University

Criteria

Inclusion Criteria:

• Pregnant women who are scheduled for cesarean section under general anesthesia (pregnant women who do not use magnesium) and who use magnesium for prophylaxis in preeclampsia.

Exclusion Criteria:

• Eclampsia,

• chronic hypertension,

• connective tissue disorder,

• muscle disease, neurological problems,

• thyroid dysfunction,

• kidney disease, heart disease,

• patients with severe allergic reaction to the agents to be used,

• sepsis,

• hypovolemia, abruptio placenta, placenta previa,

• conditions that will prolong the effect of muscle relaxants (drug use ),

• pregnant women who did not want to be included in the study