The Effect of Melatonin Application Following Removal of Impacted Third Molar

• Status: Completed
• Trial end date: 2021-05-01
• Target enrollment: 0
• Participant gender: All

Summary

In the present study, the main hypothesis hypothesizes that the local application of melatonin in the post-extraction socket produces favorable differences in the immediate postoperative period, as anti-inflammatory, analgesic, and early osteogenic regarding the natural healing process of the socket.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fayoum University
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• Age ≥18ys

• no systemic disease

• impacted mandibular third molar class II position B on Pell- Gregory classification

Exclusion Criteria:

• history of metabolic or systemic diseases affecting bone or healing process,

• local infection,

• tobacco use,

• oral contraceptive,

• pregnancy and lactation

• patients who had taken analgesics or anti-inflammatories for 1 week prior to enrollment in the study