The Effect of Metformin on Composition of Human Gut Bacteria
Status:
Completed
Trial end date:
2016-02-01
Target enrollment:
Participant gender:
Summary
OBJECTIVE: Investigate structural changes in the human gut microbiota and associated changes
in metabolic markers in urine, saliva, blood and fecal samples following metformin treatment.
DESIGN: An, 18 week, one-armed cross over intervention trial consisting of a 6-week
pre-intervention period, 6-week intervention period and a 6-week post-intervention period. 25
healthy young men will be included in the trial.
INTERVENTION: Six-week Metformin treatment to young healthy men.