The Effect of Mifepristone on Uterine Fibroids and Breast Tissue
Status:
Completed
Trial end date:
2007-06-01
Target enrollment:
Participant gender:
Summary
Uterine fibroids are a benign but common condition among women in reproductive age. It is one
of the most common reasons for hysterectomy since it often causes bleeding problems sometimes
leading to anemia. Several alternative treatment regimens have been investigated that could
replace surgery. The antiprogesterone, mifepristone, is one of the most promising drugs that
have been tested. In addition to the inhibiting effect on the growth of uterine fibroids
antiprogestins have been proposed to have an antiproliferative effect on breast tissue.
The purpose of the present study is to evaluate the effect of mifepristone on the volume of
uterine fibroids. The study will also address the effect of mifepristone on the breast tissue