The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications
for providing pain control in children with fractures or those who have surgery to correct
bony deformity requiring the bone to be cut (osteotomy) and realigned. There is some data to
suggest that these types of medications can adversely affect bone healing in adult patients
with broken bones or those having spine fusion surgery. There is little data with regard to
how these medications effect bone healing in children. With this project, the investigators'
goal is to determine if NSAIDs delay or otherwise adversely effect bone healing and to
demonstrate that these medications adequately control pain in children with broken bones or
those who have had an osteotomy.