The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure
Status:
Terminated
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
A diet rich in Omega-3 (fish oil) reduces plasma triglycerides and the risk for ischemic
heart disease. Recently, a large trial evaluating treatment with Omega 3 in heart failure
patients suggested that omega 3 may lower the risk of death from CHF. The mechanism of this
potential benefit is not well understood.
Methods:
Forty patients will be enrolled in the study. Twenty patients will receive Omega 3 (lovaza 4
gm a day) and 20 patients will receive placebo. All subjects will have assessment of their
exercise capacity and blood vessel function before and after an 8 week treatment period.
About 4 table spoons of blood will be drawn throughout the study.
Expected results:
The investigators believe that omega 3 may improve the ability to exercise and improve blood
vessel function.