Overview

The Effect of Opioid Free Anesthesia in Bariatric Surgeries

Status:
Completed

Trial end date:
2020-06-15

Target enrollment:
0

Participant gender:
All

Summary

This is a prospective randomized controlled study that will be carried out on morbid obese patients admitted to Tanta University hospitals for laparoscopic bariatric surgeries. The patients will be randomly assigned into;- Control group:- Anesthesia will be induced by fentanyl 1 ug/kg, propofol 2 mg/kg, and rocuronium 1 mg/kg to facilitate tracheal intubation. Anesthesia will be maintained by sevoflurane 2% in a mixture of oxygen: Air 1: 1 to maintain entropy 40-60. Opioid free anesthesia group;- Anesthesia will be induced by propofol 2 mg/kg, rocuronium 1 mg/kg to facilitate tracheal intubation. After endotracheal intubation, and a combination of dexmedetomidine and ketamine infusion. Anesthesia will be maintained by sevoflurane 2% in a mixture of oxygen: Air 1: 1 and continuing the infusion of dexmedetomidine and ketamine o maintain entropy 40-60.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Tanta University

Collaborator:

Mohamed Elsayed Afandy

Treatments:

Analgesics, Opioid
Anesthetics
Dexmedetomidine
Fentanyl
Ketamine
Propofol
Rocuronium
Sevoflurane

Criteria

Inclusion Criteria:

- Morbid obese patients with BMI 40-50 kg/m2

- Aged more than 21 years and American Society of Anesthesiologists Class III

- Presented for laparoscopic sleeve gastrectomy or gastric bypass.

Exclusion Criteria:

- Patients refused to participate.

- Patients with known or suspected or known allergy to the used medication.

- Patients with moderate to severe obstructive sleep apnea

- Patients with uncontrolled blood sugar, cardiac, renal, or hepatic functions.

- Patients receiving opioids preoperatively

- Uncooperative patients

- Patients received preoperative gabapentoids.