The Effect of Oral Pregabalin on Epidural-induced Shivering and Epidural Characteristics
Status:
Completed
Trial end date:
2018-11-15
Target enrollment:
Participant gender:
Summary
- Background: The previous reports tried to reduce shivering and improve neuroaxial
anesthesia characteristics by the systemic use of different drugs. This study was
directed to evaluate the effect of pregabalin premedication on both shivering and
epidural outcome data following single shot loading.
- Patients and Methods: Eighty patients, ASA grade I and II, undergoing surgeries under
epidural anesthesia were studied. The patients were divided into two groups: Pregabalin
group and Control group in which the patients received 150 mg of pregabalin and placebo
capsules respectively sixty minutes prior to surgery. Following epidural loading, the
onset and degree of shivering were compared between the two groups. Also, the epidural
outcome including onset, level and duration were traced and compared. The perioperative
hemodynamics, sedation scores, patient satisfaction and side effects were followed up
and registered.