The Effect of Orally Administered L- Arginine on Quadriceps Strenght in Healthy Smokers

• Status: Recruiting
• Trial end date: 2022-02-17
• Target enrollment: 0
• Participant gender: All

Summary

The study will investigate changes in certain locomotor parameters as early predictors of disease in smokers who are prone to develop chronic obstructive pulmonary disease (COPD).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Goranka Radmilović

Criteria

Inclusion Criteria:

• aged 40-65

• smokers and non-smokers, All patients will make spirometry and the Tiffeneau-Pinelli index (ratio of forced expiratory volume in 1 second - FEV1 and forced vital capacity FVC)> 75% of the predictive value will be taken as an inclusion criteria.

Exclusion Criteria:

• FEV1 / FVC <75%,

• inflammatory rheumatic diseases,

• malignancies,

• acute and severe heart or lung disease,

• unregulated hypertension,

• patients who have undergone major surgery in the past year,

• patients with implanted hip, knee or ankle prosthesis, will be excluded from the study.