The Effect of Perioperative of DEXamethasone on Postoperative Complications After PANcreaticoduodenectomy

• Status: Recruiting
• Trial end date: 2024-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of this clinical trial is evaluate the effect of dexamethasone on postoperative complications after pancreaticoduodenectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ruijin Hospital
• Treatments: Dexamethasone

Criteria

Inclusion Criteria:

1. Adult patients ≥18 years of age;

2. An indication for elective PD surgery;

3. Patients understand the nature of this trial and are willing to comply;

4. Patients are able to provide written informed consent;

Exclusion Criteria:

1. Current or recent (within preceding 1 month) systemic use of glucocorticoids;

2. Distant metastases including peritoneal carcinomatosis, liver metastases, distant lymph node metastases, and involvement of other organs;

3. Patients may undergo left, central, or total pancreatectomy other than PD;

4. Palliative surgery；

5. Patients with high operative risk, as defined by the American Society of Anesthesiologists (ASA), with a score ≥ 4;

6. Synchronous malignancy in other organs or second cancer requiring resection during the same procedure;

7. Pregnant and lactating women.